Top 5 Best Anti-Inflammatory Creams Available Over-The-Counter

This article was reviewed by Dr. Emilija Ashtalkoska on August 10th, 2018. Products listed therein are not intended to diagnose, treat, cure, or prevent any disease or health condition.

Overview

Experiencing inflammation is a truly terrible experience. Dermatitis, the medical term for inflammation, is all-too-common for people from all walks of life.

The most common source is from coming into direct contact with an irritant, which leads to the inflammation, swelling, redness, and even a rash.

Fortunately, we have compiled a list of the top five best anti-inflammatory creams that are available over the counter. If you are finally ready to get relief from your inflammation, continue reading below.

Do you not have a lot of time? Click here to view our top choice, Penetrex Pain Relief Cream, on Amazon.com.

Product Image
Product Name
Summary
Price
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Penetrex Joint & Muscle Therapy – Soothing Comfort for Back, Neck, Hands, Feet – Premium Whole Body Rub...
Penetrex Pain Relief Cream
One of the most popular anti-inflammatory creams in the world, made in the USA, 100% money back guarantee
Economy

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ASUTRA Relief Cream, 3 oz - Cooling Sensation, Temporary Relief from Muscle Discomfort and Soreness, 4%...
ASUTRA FDA Registered Topical Pain Relief Cream
FDA Registered inflammation and pain cream with natural ingredients
Economy

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Topricin Pain Relief Therapy Cream (2 oz) Fast Acting Pain Relieving Rub
Topricin Pain Relief Therapy Cream
Best budget anti-inflammatory cream, features 11 natural bio-medicines
Budget

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Pain Relief Cream ,Recovery Sans Hemp [4 oz] MAXIMUM STRENGTH - ALL NATURAL Anti-Inflammatory Cream For...
Absolute Earth Flex Magic Cream
Powerful anti-inflammatory cream with over 30 natural ingredients
Economy

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THERAGOLD Pain Relief Cream with Manuka Honey - 2 oz - Rapid Response, Bleach-Free, All-Natural...
Theragold All Natural Anti-Inflammatory Cream
All-natural inflammation cream, steroid, bleach, and DMSO free
Economy

Shop Now At Amazon.com

Our Top Choice – 1. Penetrex Pain Relief Cream  

Penetrex Joint & Muscle Therapy – Soothing Comfort for Back, Neck, Hands, Feet – Premium Whole Body Rub...

Penetrex Pain Relief Cream is one of the most popular anti-inflammatory creams in the world, and for good reason.

The formula is extremely powerful, works with inflammation all over the body, and actually helps treat the source of the inflammation, not just mask it.

Penetrex utilizes clinically proven ingredients such as Arnica, MSM, Vitamin B6, Choline, and Boswellia Serrata into your inflamed skin and provides relief.

There are no Parabens, no steroids in the formula, no unpleasant odor, and no grease to deal with.

The solution is manufactured in the U.S.A, and best of all has a 100% no question asked money-back guarantee.

When taking into account all of these various factors, we strongly believe that Penetrex Pain Relief Cream is the best over-the-counter anti-inflammatory cream on the market today.

The formula is available in a 2 oz. jar and a 4 oz. jar.

Click here to view Penetrex Pain Relief Cream on Amazon.com

2. ASUTRA FDA Registered Topical Pain Relief Cream

ASUTRA Relief Cream, 3 oz - Cooling Sensation, Temporary Relief from Muscle Discomfort and Soreness, 4%...

ASUTRA FDA Registered Topical Pain Relief Cream is a powerful pain and anti-inflammatory cream.

The ASUTRA solution quickly penetrates your inflamed skin and starts providing relief by promoting healthy circulation, healing, and recovery.

The solution contains Tea Tree Oil, Vitamin B6, MSM, Vitamin E, Aloe Extract, Arnica, and more.

These incredible natural ingredients come together to both provide relief and help treat your underlying inflammation.

One of our favorite things about this product is that it includes an awesome pain relief cooling roll-on solution in the packaging.

This provides powerful, fast-acting relief from inflammation, and like the ASUTRA Pain Relief Cream, contains all-natural ingredients.

Click here to view ASUTRA FDA Registered Topical Pain Relief Cream on Amazon.com

3. Topricin Pain Relief Therapy Cream

Topricin Pain Relief Therapy Cream (2 oz) Fast Acting Pain Relieving Rub

Topricin Pain Relief Therapy Cream touts itself as being the best alternative to prescription and non-prescription medicines that are taken orally.

This means that it is a fantastic choice for anyone who suffers from inflammation, headaches, nerve pain, and more serious diseases such as arthritis and shingles.

Perhaps most impressively, Topricin even claims to be safe for use by pregnant mothers, children, and elderly. However, we recommend always consulting your doctor before using a topical treatment.

Topricin Pain Relief Therapy Cream is also notable because it has no offensive odor, making it a great choice for those inflammation sufferers who have sensitive noses.

Additionally, Topricin is made in the U.S.A. This is one of the best pain relief products on the market today.

Click here to view Topricin Pain Relief Therapy Cream on Amazon.com

4. Absolute Earth Flex Magic Cream

Pain Relief Cream ,Recovery Sans Hemp [4 oz] MAXIMUM STRENGTH - ALL NATURAL Anti-Inflammatory Cream For...

Absolute Earth Flex Magic Cream is an incredible over-the-counter anti-inflammatory cream.

Arnica, Boswellia, MSM, Vitamin B6, and more all come together to help provide relief from inflammation and pain.

Flex Magic Cream helps aid the body’s natural healing mechanism – it doesn’t just mask the pain like many other inflammation creams do.

Simply rub the formula deep into the affected area four to five times a day, and eventually, you should start to see results.

The solution was crafted by top-of-the-line researchers in an FDA certified laboratory.  Additionally, the cream is cruelty-free, paraben free, chemical free, and preservative free.

Click here to view Absolute Earth Flex Magic Cream on Amazon.com

5. Theragold All Natural Anti-Inflammatory Cream

THERAGOLD Pain Relief Cream with Manuka Honey - 2 oz - Rapid Response, Bleach-Free, All-Natural...

Theragold All-Natural Solution is an incredible, all-natural anti-inflammatory cream that appeals to those dermatitis sufferers who want to be more in tune with nature.

The formula is comprised of completely natural, inflammation-fighting ingredients that are found in the wild. This includes Ginger, Arnica, Cayenne, Peppermint, Calendula, Manuka Honey, and Clary Sage.

These powerful ingredients work together to fight off your inflammation and give provide you with relief.

Additionally, these natural ingredients blend together to create a pleasant, natural-smelling odor that goes away after a few minutes.

The fine folks at Theragold are serious about providing a natural solution that is good for the largest organ on your body – your skin!

The solution is completely steroid, bleach, and DMSO free. Additionally, they have an awesome, 100% refund policy if you are unhappy with the solution.

Click here to view Theragold All Natural Anti-Inflammatory Cream on Amazon.com

How To Apply Anti-Inflammatory Cream To Your Skin

Utilizing a topical non-steroidal anti-inflammatory cream is quite simple.

Although directions and dosages will differ between products, the general outline is the same. Consult a medical professional before using a new treatment.

1. Test Your Reaction

It is always a great idea to test your reaction before introducing yourself to a new treatment, inflammation cream or otherwise.

Simply apply a small amount of cream to a portion of your skin that is not inflamed, and rub it in completely.

Wait upwards of ten minutes to see if there is any sort of negative reaction. If so, consult your doctor immediately and stop use.

2. Apply The Cream To Your Skin

Once you have tested your reaction to the cream, simply apply a generous amount of cream to your inflamed areas and rub it in completely.

Once the cream has been applied, please thoroughly wash your hands.

Different people respond differently to different solutions, but depending on which anti-inflammatory cream you have chosen and your body’s reaction, you may experience relief in as little as five minutes. 

For others, it may take a bit longer.

3. Keep Applying The Solution As Needed

The directions differ slightly between creams, but most advise continuing to use the cream multiple times per day until the underlying reason for the inflammation goes away.

If this does not happen after a reasonable time frame, please consult your doctor.

Will These Anti-Inflammatory Creams Work For Tendonitis, Back Pain, Shingles, Etc?

anti inflammatory cream over the counter

Yes, these anti-inflammatory creams should provide you with relief from your tendonitis, fibromyalgia, carpal tunnel, sore muscles, nerve pain, back pain, and even arthritis.

However, we insist that you consult your doctor or a medical professional before introducing any new medicine or cream to your body.

Are There Any Possible Side-Effects From Using Anti-Inflammatory Creams?

Although side-effects are rare, it is possible to have an adverse reaction to any of the ingredients in these topical solutions.

The most likely scenario is that it aggravates your skin more, causing it to become more inflamed.

However, more serious side-effects are possible. Consult your doctor before introducing any topical solution or cream to your skin.

Should I Use These Creams If I Am Pregnant?

We highly recommend consulting your doctor or a medical professional before using any of these creams, especially if you are pregnant.

Where Should I Purchase Anti-Inflammatory Cream?

Many of our readers have asked us where they should purchase anti-inflammatory creams over the counter – they wonder if they should go to CVS, Walmart, Walgreens, or another retailer.

We highly believe that the best place to make your purchase is on Amazon.com. Click here to view the product page of our top choice, Penetrex Pain Relief Cream, on Amazon.com.

Conclusion

Inflammation is terrible, but you do not have to let it take over your life.

There are a number of great topical creams on the market today that can provide inflammation relief for your back pain, shingles, sciatica, injuries, sprains, and more.

Whatever the reason is for your inflammation, the incredible creams on this list will be able to help give you relief.

Feel free to leave a question or comment below, and best of luck with your inflammation-fighting journey.


References

Sources for more information on anti-inflammatory creams: